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Sepsis Digital PCR (dPCR) Detection Kit
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Sepsis Digital PCR (dPCR) Detection Kit

The Aperbio Sepsis Digital PCR (dPCR) Solution is an advanced molecular diagnostic tool designed for the early identification of pathogens and antimicrobial resistance (AMR) genes directly from blood samples. By leveraging micro-fluidic chip dPCR technology, this solution achieves absolute quantification and high sensitivity, detecting even single-copy targets that traditional methods might miss.

    Key Advantages and Benefits

    Rapid Reporting: 
    Delivers results in ~3–4 hours, significantly faster than the 24–72 hours required for traditional blood cultures.

    High Sensitivity & Specificity: 
    Increases the pathogen positivity rate to >48% (a 2.9x increase over blood culture). It is effective even for low-load infections or patients already on antibiotics.

    Absolute Quantification: 
    Unlike qPCR, dPCR provides absolute concentrations without a standard curve, enabling precise monitoring of disease progression.

    High Tolerance: 
    The partitioned reaction system minimizes interference from inhibitors in complex blood matrices.

    User-Friendly Automation: 
    A streamlined workflow from sample to result reduces manual steps and minimizes contamination risks.

    Clinical Value

    Early Intervention:
    By providing pathogen evidence during the first ward rounds, clinicians can transition from "empirical medication" to "precision treatment" sooner.

    Precision Antibiotic Stewardship: 
    Facilitates targeted therapy by identifying resistance genes within hours, reducing unnecessary broad-spectrum antibiotic use and slowing the rise of resistance.

    Improved Patient Outcomes:
    Quantitative monitoring allows for real-time assessment of treatment response and early warning of disease deterioration.

    Cost Reduction: 
    Aids in early diagnosis, which can shorten hospital stays and reduce overall hospitalization costs by approximately 50%.

    Application Scenarios

    Emergency & ICU: 
    Ideal for critically ill patients (sepsis, septic shock) where rapid decision-making is vital.

    Immunocompromised Patients:
     Early screening for infections in patients undergoing chemotherapy, organ transplants, or those with autoimmune disorders.

    Difficult-to-Diagnose Cases: 
    Patients with FUO (Fever of Unknown Origin) or those who test negative via traditional cultures.

    Dynamic Monitoring: 
    Real-time tracking of pathogen load to evaluate the efficacy of antimicrobial therapy.

    Workflow: From Sample to Report

    The integrated workflow is designed for speed and accuracy, typically completing in 3–4 hours

    1

    Ordering Information

    Catalog No.

    Product Name

    Specification

    Description

    123021048

    Sepsis-28 with AMR Digital PCR Detection Kit

     48r

    Chip matched



    We have a variety of reference materials available, including colour brochures, technical guides, professional literature and operation videos. If you need to consult or obtain relevant materials, please fill in the information below to contact us.