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Organoids

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Organoids

Organoids represent an innovative technology that can summarize the physiological processes of the entire organism, with advantages such as being closer to physiological cell composition and behavior, more stable genome, and more suitable for biological transfection and high-throughput screening. Compared with animal models, organoid models are simpler to operate and can also be used to study the mechanisms of disease occurrence and development. Therefore, they have broad application prospects in the fields of organ development, precision medicine, regenerative medicine, drug screening, gene editing, disease modeling, etc.

Solution

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    Establishment of organoid model

    In the process of organoid culture, it is essential to monitor the growth status of the cultures at regular intervals. Aperbio's Echo intelligent microscopy system is an integrated system designed to handle a variety of sample types. It facilitates the observation of organoid morphology throughout the culture process. With its user-friendly and intelligent software interface, it streamlines the observation process, saving valuable time and labor.

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    Organoid identification

    Organoids are typically characterized by HE staining, immunohistochemistry, and immunofluorescence. Aperbio's Echo integrated intelligent microscopy system is equipped to handle up to four fluorescent channels, enabling high-resolution imaging and scanning. This versatile system consolidates multiple functionalities into a single device, adeptly catering to the diverse needs of various detection methods.

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    Application of organoid models

    Organoids offer extensive applications, including tumor diagnosis and therapy, drug development, exploration of developmental mechanisms, disease pathogenesis, genetic and toxicological studies, and pathogen research. Aperbio's Echo intelligent microscopy system is designed to meet the diverse imaging observation requirements across these applications. Additionally, Aperbio's Naica digital PCR system delivers a comprehensive solution for the detection of nucleic acids, facilitating detailed analyses of genomic, transcriptomic, and epigenetic information.

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    Quality and Safety

    The organoid quality standards are not yet universally agreed upon in the industry. Aperbio offers comprehensive solutions for organoid quality assessment, covering aspects such as morphology, histopathology, and molecular genetics. Leveraging our proprietary technology and R&D capabilities, we can support the advancement of methodologies in this field.

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