Clinical Diagnostics

Clinical solution for accurate detection of lung cancer

Lung cancer is one of the most common malignant tumors in the world. Lung cancer ranks first in both morbidity and mortality worldwide. In China, there are about 828,000 new cases of lung cancer and about 715,000 deaths each year. According to histological classification, it can be divided into small cell lung cancer and non-small cell lung cancer. About 80% of lung cancer is non-small cell lung cancer, and about 75% of patients are already in the middle and late stages when diagnosed.

818K

Incidence/No.1

715K

Mortality/No.1

Core driver genes of lung cancer and clinical value

	First Generation	Second Generation	Three generations
EGFR	Gefitinib, Erlotinib, Ecatinib	Afatinib, Dacotinib	Axitinib, Amitinib, Fumatinib, etc
KRAS	Sotolabu, Adagrasibu
BRAF	Dabrafenib, Trametinib
PIK3CA	Mutations that affect the efficacy of EGFR-TKIs
NRAS	MEK inhibitors
NTRK	Larotrectinib、Entrectinib
ALK	Crizotinib	Alectinib, Ceritinib Brigatinib, Ensartinib	Lorlatinib
ROS1	Crizotinib, ceritinib, lorlatinib, entrectinib
HER2	DS-8201（trastuzumab deruxtecan, T-DXd), Pyrotinib
MET	Tepotinib, Capmatinib, Sirolimus, Gumetinib, etc.
RET	Selpercatinib、Pratinib

Ordering Information

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121005024 EGFR Gene Mutations Digital PCR Detection Kit

121003024 EGFR T790M Mutation Digital PCR Detection Kit

121004024 EGFR T790M and C797S cis/trans Mutations Digital PCR Detection Kit

121007024 KRAS G12/G13 Mutations Digital PCR Detection Kit

121021024 KRAS G12A&G12D Mutations Digital PCR Detection Kit

121022024 KRAS G12C&G12V Mutations Digital PCR Detection Kit

121023024 KRAS G13D Mutation Digital PCR Detection Kit

121001024 BRAF V600E/V600K/V600R Mutations Digital PCR Detection Kit

121017024 NRAS G12/G13 Mutations Digital PCR Detection Kit

121014024 ALK/RET/MET14 Gene Fusion Digital PCR Detection Kit

121008024 HER2 Gene Amplification/Exon 20 Insertion Mutation Digital PCR Detection Kit

121009024 PIK3CA Gene Mutations Digital PCR Detection Kit

121013024 NTRK Gene Fusion Digital PCR Detection Kit

121012024 ALK Gene Fusion Digital PCR Detection Kit

121011024 ROS1 Gene Fusion Digital PCR Detection Kit

121006024 HER2 Gene Amplification Digital PCR Detection Kit

Equipment and Supplies

N10001.3 Naica® digital PCR system-3 color

N10001.6 Naica® digital PCR system-6 color

N30027.0 Nio™+Ultimate dPCR

C16011 Ruby Chips

C14012 Sapphire Chips

*For research use only

Workflow

Sample type: blood/fresh tissue

Sample collection

Nucleic acid extraction, PCR system configuration and sample addition

Droplet generation and expansion

Result analysis

Platform