naica® digital PCR helps analyze the immune responses of different systems and mucosa during acute SARS-CoV-2 infection

The Pasteur Institute in France published a high scoring article (NATURE IMMUNOLOGY, IF: 25.6) using the naica from Stilla Technologies in France ® The micro drop chip digital PCR system and Apebbe biological Apexbio COVID-19 digital PCR detection kit quantify the load of COVID-19 in plasma.

The discovery of COVID-19 new variety Omicron in South Africa on November 24 has once again aroused people's attention to COVID-19. The most special thing about Omicron is that it has 15 mutation sites in RBD (receptor binding domain), while Delta has only two, and there are only three Beta known for its immune escape ability. This is a serious challenge to the existing treatment scheme and vaccine scheme. The previously widely concerned regenerative neutralizing antibody combination therapy has been declared invalid for Omicron. These facts show that we need to have a deeper understanding of the pathological and immune responses generated by COVID-19 to help us overcome the epidemic.

Recently, scientists from the Pasteur Institute in France used naica ® The technology of micro drop chip digital PCR system, cytokine detection, etc., published an article on NATURE IMMUNOLOGY (IF: 25.6) to systematically analyze the immune response of COVID-19 after it enters the human body, and explored the potential relationship between the microbial community and COVID-19, further unlocking the immune characteristics of the human body against COVID-19.

Highlights

1.naica ® The micro drop chip digital PCR system detects the load of COVID-19 in plasma and confirms that it is related to the course of disease

2. The load of COVID-19 in different tissues is not completely consistent with the degree of symptoms

3. The nasal microbiome affects the local mucosal and systemic immune responses of COVID-19 patients