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Aegaeon® Digital PCR System (Model: XW Dx）
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Aegaeon® Digital PCR System (Model: XW Dx）

The Aegaeon® Digital PCR System leverages advanced droplet digital PCR (ddPCR) technology to provide high-precision, single-molecule analysis. By partitioning samples into thousands of discrete reaction units, the XW Dx enables absolute quantification without standard curves. This integrated platform automates droplet generation, amplification, and multi-channel detection, delivering superior sensitivity and reliability for clinical diagnostics

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    Key Advantages and Benefits

    Integrated Workflow: Carries out the entire dPCR process—droplet generation, amplification, and detection—on a single chip to minimize contamination risks

    High Precision & Absolute Quantification: Delivers accurate quantification without the need for standard curves or PCR efficiency calibrations.

    Exceptional Stability: Advanced technology ensures the production of uniform, stable droplets for consistent results.

    Modular Flexibility: Features three independent temperature control modules, allowing for the simultaneous execution of multiple PCR programs.

    Superior Sensitivity: Enhanced capability for detecting trace amounts of nucleic acids and low-abundance targets, even in complex background samples with high inhibitor resistance.

    Visual Quality Control: Intuitive software enables comprehensive, visually guided monitoring of droplet formation and signal detection to ensure data reliability.

    Clinical and Research Applications

    Leveraging a sophisticated research framework, the system supports a wide array of applications:

    Oncology: Detection of rare mutations (e.g., EGFR, KRAS, BRAF), gene fusions, and Copy Number Variation (CNV) analysis for efficacy monitoring and cancer screening.

    Infectious Diseases: Absolute quantification of viral and bacterial loads, including COVID-19, Influenza, and HIV-1 latent reservoirs.

    Hematological Disorders: Monitoring of fusion genes like BCR-ABL1 and mutations in JAK2 or BTK.

    Advanced Treatments: Support for gene editing validation, epigenetics, and mRNA expression analysis.

    Prenatal Screening: Accurate detection of genetic markers for prenatal diagnostics.

    Workflow

    Fully Automated Workflow: Reproducible Results, Reduced Labour, Increased Efficiency.

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    Technical Specifications

    Feature

    Specification

    Model

    XW Dx

    Throughput

    1–48 samples per run

    Detection Channels

    3-color fluorescence

    Droplet Uniformity

    CV < 3.5% (AutoRuby Dx) vs 7.5% (Manual)

    Reaction Volume

    5 µL reaction mix

    Droplet Count

    Average 20,000 droplets per 5 µL

    Interface

    14.5-inch Touch-screen

    Quantification Precision

    Concentration CV < 2.4% (AutoRuby Dx)

    Ordering Information

    Catalog No.

    Product Name

    Model

    Description

    H631104

    Aegaeon®Digital PCR System

    XW Dx

    CE-IVD, 1–48 samples per run, 3-color fluorescence, average 20,000 droplets per 5 µL.

    If you need any additional materials such as color pages, technical guides, professional literature and operation videos, please fill in the following information and contact us.